GHK-Cu
1700 mcg · Daily, PM
Evidence
- Human Studies
- 20
- Animal Studies
- 60
- Clinical Status
- Research
- Confidence
- Low
- Long-Term Safety
- Better established topically; limited data for injectable/systemic long-term use
What this score is: a measure of how much research exists and how far along it is (animal-only vs. human trials, research-stage vs. FDA approved) — not how safe, effective, or worth trying a compound is. A low score usually means “early stage” or “understudied,” not “bad.” A high score doesn’t mean “better” for your goals than a lower-scored one.
This is not my personal rating of the compound, not a recommendation, and not medical advice. It’s a general research synthesis for informational purposes only, not a live literature count. See the linked research and talk to a licensed clinician before making decisions based on it.
Mechanism
GHK-Cu is a naturally occurring copper-binding peptide studied for roles in collagen/elastin production and wound healing. It is well studied topically in cosmetic dermatology; injectable/systemic use is far less researched.
Common Protocols
- 1–2 mg daily, subcutaneous, typically PM
- Also widely used topically in skincare formulations (different evidence base than injection)
Side Effects
- Injection site irritation
- Topical formulations occasionally cause skin irritation
Interactions
- Copper-containing supplements/multivitamins may compound total copper intake — track separately
Practical Details
- Cost
- $$
- Typical Vial Size
- 50 mg
- Storage
- Refrigerate after reconstitution
Research Links
PM daily for overnight tissue repair